Mometasone

Mometasone is an inhaled glucocorticoid. Mometasone can be used in mild asthma with a low sputum eosinophil level. Mometasone has the potential for the research of chronic hand eczema and rhinosinusitis[1][2].

Product Specifications

CAS Number

[105102-22-5]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Glucocorticoid Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/mometasone.html

Purity

99.46

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

Cl[C@@]1([C@]2(C=C3)C)[C@](CCC2=CC3=O)([H])[C@@](C[C@@H](C)[C@]4(O)C(CCl)=O)([H])[C@]4(C)C[C@@H]1O

Molecular Formula

C22H28Cl2O4

Molecular Weight

427.36

Precautions

H302, H315, H319, H335

References & Citations

[1]Veien NK, et al. Long-term, intermittent treatment of chronic hand eczema with mometasone furoate. Br J Dermatol. 1999 May;140 (5) :882-6.|[2]Lazarus SC, et al. Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level. N Engl J Med. 2019 May 23;380 (21) :2009-2019.|[3]Wyss D, et al. Synergistic effect of formoterol and mometasone in a mouse model of allergic lung inflammation. Br J Pharmacol. 2007 Sep;152 (1) :83-90.