ML-184
ML-184 (CID244033) is a selective GPR55 agonist with an EC50 of 250 nM, more than 100-fold selectivity for GPR55 over GPR35, CB1, and CB2. ML-184 induces ERK1/2 phosphorylation and PKCβII translocation to the plasma membrane via activation of GPR55. ML-184 (CID2440433) increases the proliferation of neural stem cells and promotes neuronal differentiation in vitro[1][2][3].
Product Specifications
CAS Number
794572-10-4
Product Name Alternative
CID2440433
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
GPR55
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ml-184.html
Purity
99.57
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1=CC=CC(N2CCN(CC2)C(C3=CC(S(N(C)C)(=O)=O)=CC=C3N4CCCC4)=O)=C1C
Molecular Formula
C25H34N4O3S
Molecular Weight
470.63
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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