Rostratin A
Product Specifications
UNSPSC Description
Rostratin A is a cytotoxic disulfide found in the marine-derived fungus Exserohilum rostratum. Rostratin A shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with an IC50 of 8.5 μg/mL[1].
Target Antigen
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rostratin-a.html
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@]([C@H](CC2)O)([H])[C@]([C@H]2O)([H])C3)[C@@]4(SS[C@]13C5=O)N5[C@@]([C@H](CC6)O)([H])[C@]([C@H]6O)([H])C4
Molecular Weight
428.52
References & Citations
[1]Tan RX, et al. Isolation and structure assignments of rostratins A-D, cytotoxic disulfides produced by the marine-derived fungus Exserohilum rostratum. J Nat Prod. 2004;67(8):1374-1382.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N10203/Rostratin-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N10203/
Clinical Information
No Development Reported
CAS Number
752236-16-1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
