Rostratin A
Rostratin A is a cytotoxic disulfide found in the marine-derived fungus Exserohilum rostratum. Rostratin A shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with an IC50 of 8.5 μg/mL[1].
Product Specifications
CAS Number
752236-16-1
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rostratin-a.html
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@]([C@H](CC2)O)([H])[C@]([C@H]2O)([H])C3)[C@@]4(SS[C@]13C5=O)N5[C@@]([C@H](CC6)O)([H])[C@]([C@H]6O)([H])C4
Molecular Formula
C18H24N2O6S2
Molecular Weight
428.52
References & Citations
[1]Tan RX, et al. Isolation and structure assignments of rostratins A-D, cytotoxic disulfides produced by the marine-derived fungus Exserohilum rostratum. J Nat Prod. 2004;67 (8) :1374-1382.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Microbial Metabolite
Frequently Asked Questions
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