5-Nitro-DL-tryptophan (Highly Pure)

<strong>5-Nitro-DL-tryptophan (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2016218_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 250 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 249.23 g/mol_x000D_ <strong>Supplied as:</strong> Solution When Dissolved_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> DL-2-Amino-3-(5-nitroindolyl)propionic acid; H-5-Nitro-DL-Trp-OH_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Choi JS, Kim CS, Berdis A. Inhibition of Translesion DNA Synthesis as a Novel Therapeutic Strategy to Treat Brain Cancer Cancer Res. 2018 Feb 15;78(4):1083-1096._x000D_ 2: Choi JS, Berdis A. Artificial Nucleosides as Diagnostic Probes to Measure Translesion DNA Synthesis Methods Mol Biol. 2019;1973:237-249._x000D_ 3: Motea EA, Lee I, Berdis AJ. A non-natural nucleoside with combined therapeutic and diagnostic activities against leukemia ACS Chem Biol. 2012 Jun 15;7(6):988-98._x000D_ 4: Motea EA, Lee I, Berdis AJ. Development of a 'clickable' non-natural nucleotide to visualize the replication of non-instructional DNA lesions Nucleic Acids Res. 2012 Mar;40(5):2357-67._x000D_ 5: Reineks EZ, Berdis AJ. Evaluating the contribution of base stacking during translesion DNA replication Biochemistry. 2004 Jan 20;43(2):393-404._x000D_ 6: Ahmad MF, Wan Q, Jha S, Motea E, Berdis A, Dealwis C. Evaluating the therapeutic potential of a non-natural nucleotide that inhibits human ribonucleotide reductase Mol Cancer Ther. 2012 Oct;11(10):2077-86._x000D_ 7: Wu X, Ma X, Zhong Y, Chen W, Xu M, Zhang H, Wang L, Tu X, Han Z, Zhao W, Wu Z, Moschos SJ, Li Z. Development of [(18)F]F-5-OMe-Tryptophans through Photoredox Radiofluorination: A New Method to Access Tryptophan-Based PET Agents J Med Chem. 2023 Mar 9;66(5):3262-3272._x000D_ 8: Shirmovsky SE, Chizhov AV. Modeling of the entangled states transfer processes in microtubule tryptophan system Biosystems. 2023 Sep;231:104967._x000D_ 9: Zou Y, Yu L, Fang X, Zheng Y, Yang Y, Wang C. Position-coded multivalent peptide-peptide interactions revealed by tryptophan-scanning mutagenesis J Pept Sci. 2020 Sep;26(9):e3273._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/37976523">10: Richaud AD, Mandal S, Das A, Roche SP. Tunable CH/π Interactions within a Tryptophan Zipper Motif to Stabilize the Fold of Long β-Hairpin Peptides ACS Chem Biol. 2023 Dec 15;18(12):2555-2563. </a>_x000D_ _x000D_ <strong>Products Related to 5-Nitro-DL-tryptophan (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>