KGP-25
KGP-25 is an inhibitor of voltage-gated sodium channel 1.8 (Nav1.8), which can be used for analgesia by targeting Nav1.8 in the peripheral nervous system (PNS) . KGP-25 can also target γ-aminobutyric acid subtype A receptor (GABAA) in the central nervous system (CNS) for general anesthesia[1].
Product Specifications
UNSPSC
12352005
Target
GABA Receptor; Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kgp-25.html
Purity
95.0
Smiles
CC(C1=C(C(C(C)C)=CC=C1)OC(OCC[NH+](CC)CC)=O)C.[Cl-]
Molecular Formula
C19H32ClNO3
Molecular Weight
357.92
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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