Dehydrodiconiferyl alcohol

Dehydrodiconiferyl alcohol is an estrogen receptor agonist that can promote BMP-2-induced osteoblastogenesis. Dehydrodiconiferyl alcohol also exerts anti-inflammatory activity through inactivation of NF-κB pathways[1][2].

Product Specifications

CAS Number

[4263-87-0]

UNSPSC

12352005

Hazard Statement

H225, H304, H315, H319

Target

Estrogen Receptor/ERR

Type

Natural Products

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/dehydrodiconiferyl-alcohol.html

Purity

98.32

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=CC=C(C2OC3=C(C2CO)C=C(/C=C/CO)C=C3OC)C=C1OC

Molecular Formula

C20H22O6

Molecular Weight

358.39

Precautions

H225, H304, H315, H319

References & Citations

[1]Lee W, et, al. Dehydrodiconiferyl alcohol promotes BMP-2-induced osteoblastogenesis through its agonistic effects on estrogen receptor. Biochem Biophys Res Commun. 2018 Jan 15;495 (3) :2242-2248.|[2]Hu X, et, al. Dehydrodiconiferyl alcohol from Silybum marianum (L.) Gaertn accelerates wound healing via inactivating NF-κB pathways in macrophages. J Pharm Pharmacol. 2020 Feb;72 (2) :305-317.