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4-Amino-D-phenylalanine

4-Amino-D-phenylalanine ([D-Phe (4-NH2) ), a cyclic pentapeptide, inhibits CXCL12 binding to CXCR4 in FC131, with an IC50 of 0.1 μM[1].

Product Specifications

CAS Number

[102281-45-8]

Product Name Alternative

4-NH2-d-Phe

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

CXCR

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/4-amino-d-phenylalanine.html

Purity

99.74

Smiles

OC([C@H](N)CC1=CC=C(C=C1)N)=O

Molecular Formula

C9H12N2O2

Molecular Weight

180.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Hirokazu Tamamura, et al. Structure-activity relationship studies on CXCR4 antagonists having cyclic pentapeptide scaffolds. Org Biomol Chem. 2005 Dec 21;3 (24) :4392-4.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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