4-Amino-D-phenylalanine
4-Amino-D-phenylalanine ([D-Phe (4-NH2) ), a cyclic pentapeptide, inhibits CXCL12 binding to CXCR4 in FC131, with an IC50 of 0.1 μM[1].
Product Specifications
CAS Number
[102281-45-8]
Product Name Alternative
4-NH2-d-Phe
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
CXCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/4-amino-d-phenylalanine.html
Purity
99.74
Smiles
OC([C@H](N)CC1=CC=C(C=C1)N)=O
Molecular Formula
C9H12N2O2
Molecular Weight
180.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Hirokazu Tamamura, et al. Structure-activity relationship studies on CXCR4 antagonists having cyclic pentapeptide scaffolds. Org Biomol Chem. 2005 Dec 21;3 (24) :4392-4.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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