Tyrosinase-IN-31

Tyrosinase-IN-31 (compound 2-06) is a central-targeting tyrosinase inhibitor (tyrosinase: monophenolase IC50=70.44 μM, diphenolase IC50=1.89 μM) . Tyrosinase-IN-31 can inhibit the tyrosinase and melanogenesis. Tyrosinase-IN-31 can penetrate the BBB and enter the central nervous system (CNS) . Tyrosinase-IN-31 shows neuroprotective effects and Parkinsonism behavior improving function[1].

Product Specifications

CAS Number

[903206-81-5]

UNSPSC

12352005

Target

Tyrosinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tyrosinase-in-31.html

Smiles

O=C(N1CC(C=C(OC)C(OC)=C2)=C2CC1)CSC3=NC4=C(N3)C=CC=C4

Molecular Formula

C20H21N3O3S

Molecular Weight

383.46

References & Citations

[1]Qi S, et al. A new strategy for the treatment of Parkinson's disease: Discovery and bio-evaluation of the first central-targeting tyrosinase inhibitor. Bioorg Chem. 2024 Sep;150:107612.