Tyrosinase-IN-31
Tyrosinase-IN-31 (compound 2-06) is a central-targeting tyrosinase inhibitor (tyrosinase: monophenolase IC50=70.44 μM, diphenolase IC50=1.89 μM) . Tyrosinase-IN-31 can inhibit the tyrosinase and melanogenesis. Tyrosinase-IN-31 can penetrate the BBB and enter the central nervous system (CNS) . Tyrosinase-IN-31 shows neuroprotective effects and Parkinsonism behavior improving function[1].
Product Specifications
CAS Number
[903206-81-5]
UNSPSC
12352005
Target
Tyrosinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tyrosinase-in-31.html
Smiles
O=C(N1CC(C=C(OC)C(OC)=C2)=C2CC1)CSC3=NC4=C(N3)C=CC=C4
Molecular Formula
C20H21N3O3S
Molecular Weight
383.46
References & Citations
[1]Qi S, et al. A new strategy for the treatment of Parkinson's disease: Discovery and bio-evaluation of the first central-targeting tyrosinase inhibitor. Bioorg Chem. 2024 Sep;150:107612.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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