HPK1-IN-44
HPK1-IN-44 (Compound 1) is an inhibitor of HPK1 (IC50=0.1 nM (40 μM ATP) ) [1].
Product Specifications
UNSPSC
12352005
Target
MAP4K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hpk1-in-44.html
Solubility
10 mM in DMSO
Smiles
CC1(C2=CC(N3CCOCC3)=CC=C2NC4=C1C=C(C5=C4C(NC=C5)=O)C6=CN=C7C(Cl)=CC=CN67)C
Molecular Formula
C29H26ClN5O2
Molecular Weight
512.00
References & Citations
[1]Guanglong S et al. HPK1 inhibitor, preparation method therefor, and use thereof.World Intellectual Property Organization, WO2024061345 A1 2024-03-28
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAP4K1/HPK1
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