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HPK1-IN-44

HPK1-IN-44 (Compound 1) is an inhibitor of HPK1 (IC50=0.1 nM (40 μM ATP) ) [1].

Product Specifications

UNSPSC

12352005

Target

MAP4K

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/hpk1-in-44.html

Solubility

10 mM in DMSO

Smiles

CC1(C2=CC(N3CCOCC3)=CC=C2NC4=C1C=C(C5=C4C(NC=C5)=O)C6=CN=C7C(Cl)=CC=CN67)C

Molecular Formula

C29H26ClN5O2

Molecular Weight

512.00

References & Citations

[1]Guanglong S et al. HPK1 inhibitor, preparation method therefor, and use thereof.World Intellectual Property Organization, WO2024061345 A1 2024-03-28

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MAP4K1/HPK1

Frequently Asked Questions

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