PD-1-IN-24
PD-1-IN-24 (compound 1) is an orally active PD-1 inhibitor[1].
Product Specifications
CAS Number
[2360909-50-6]
UNSPSC
12352005
Target
PD-1/PD-L1
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pd-1-in-24.html
Concentration
10mM
Purity
98.12
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1=C(C2=CC=CC=C2)C=CC=C1/C=C/C3=C(C=CC(CN[C@](CO)(C)C(O)=O)=C3)C(F)(F)F
Molecular Formula
C27H26F3NO3
Molecular Weight
469.50
References & Citations
[1]Wang, Yuguang, et al. Combination of small molecule inhibitor of the PD-1/PD-L1 interaction and anti-PD-1 antibody for treatment of cancer. Patent WO 2021052386.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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