PD-1-IN-24

PD-1-IN-24 (compound 1) is an orally active PD-1 inhibitor[1].

Product Specifications

CAS Number

[2360909-50-6]

UNSPSC

12352005

Target

PD-1/PD-L1

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pd-1-in-24.html

Concentration

10mM

Purity

98.12

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC1=C(C2=CC=CC=C2)C=CC=C1/C=C/C3=C(C=CC(CN[C@](CO)(C)C(O)=O)=C3)C(F)(F)F

Molecular Formula

C27H26F3NO3

Molecular Weight

469.50

References & Citations

[1]Wang, Yuguang, et al. Combination of small molecule inhibitor of the PD-1/PD-L1 interaction and anti-PD-1 antibody for treatment of cancer. Patent WO 2021052386.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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