[K15, R16, L27]VIP (1-7) /GRF (8-27)
[K15, R16, L27]VIP (1-7) /GRF (8-27), a VIP1 selective agonist, exhibits IC50 values of binding of 2 nM, 1 nM, 30,000 nM for the human VIP1, rat VIP1, rat VIP2 receptors, respectively[1]. VIP: VASOACTIVE Intestinal Polypeptide
Product Specifications
CAS Number
201995-58-6
UNSPSC
12352209
Target
IPK Superfamily
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease; PI3K/Akt/mTOR
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/k15-r16-l27-vip-1-7-grf-8-27.html
Solubility
10 mM in DMSO
Smiles
[C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)[C@H](CC)C)=O)CC(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CC(C)C)=O)CCCCN)=O)CCCNC(=N)N)=O)C)=O)CO)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCCCN)=O)CC(C)C)=O)[C@H](C)C)=O)CCCCN)=O)CCCNC(=N)N)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CN=CN3)N)=O)CO)=O)CC(O)=O)=O)C)=O)C(C)C)=O)=O)[C@@H](C)O)=O)CC(N)=O)=O)CO)=O
Molecular Formula
C142H240N44O38
Molecular Weight
3171.70
References & Citations
[1]P Gourlet, et al. Development of high affinity selective VIP1 receptor agonists. Peptides. 1997;18 (10) :1539-45.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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