Antibacterial agent 189

Antibacterial agent 189 (compound 3a) is a potent antimicrobial agent. Antibacterial agent 189 offers high binding energy against the target OMPA/exo-1,3-beta-glucanase proteins. Antibacterial agent 189 exhibits the potent antimicrobial activities against E. coli, P. aeruginosa, S. aureus, B. subtilis, C. Albicans and A. flavus. Antibacterial agent 189 shows high binding energy against target SMO and SUFU/GLI-1 proteins[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Bacterial; Gli; Smo

Type

Reference compound

Related Pathways

Anti-infection; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-189.html

Solubility

10 mM in DMSO

Smiles

O=C1N(C2=CC=C(C3=NC4=CC=CC=C4NC(/C=C/C5=CC=CC=C5)C3)C=C2)C(C6=CC=CC=C6)=NC7=C1C=CC=C7

Molecular Formula

C37H28N4O

Molecular Weight

544.64

References & Citations

[1]Noser AA, et al. Synthesis and molecular docking simulations of novel azepines based on quinazolinone moiety as prospective antimicrobial and antitumor hedgehog signaling inhibitors. Sci Rep. 2024 Feb 12;14 (1) :3530.