(Rac) -3-Hydroxyphenylglycine

(Rac) -3-Hydroxyphenylglycine (3HPG) is a racemic mixture of (S) -3-hydroxyphenylglycine and (R) -3-hydroxyphenylglycine. (S) -3-Hydroxyphenylglycine is a potent and selective mGluR1 agonist[1][2].

Product Specifications

CAS Number

[31932-87-3]

Product Name Alternative

3HPG

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rac-3-hydroxyphenylglycine.html

Purity

99.58

Solubility

DMSO : 18.18 mg/mL (ultrasonic; adjust pH to 9 with 1M NaOH) |H2O : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(O)C(N)C1=CC=CC(O)=C1

Molecular Formula

C8H9NO3

Molecular Weight

167.16

Precautions

H302, H315, H319, H335

References & Citations

[1]E F Birse, et al. Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system. Neuroscience. 1993 Feb;52 (3) :481-8. Neuroscience. 1993 Feb;52 (3) :481-8.|[2]Y Hayashi, et al. Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. J Neurosci. 1994 May;14 (5 Pt 2) :3370-7.