Monoclonal Anti-Human tau Antibody, Mouse IgG1 (6G7C8) (MALS verified)
Tau, the microtubule‐associated protein, forms insoluble filaments that accumulate as neurofibrillary tangles in Alzheimer's disease (AD) and related tauopathies. Under physiological conditions, tau regulates the assembly and maintenance of the structural stability of microtubules. In the diseased brain, however, tau becomes abnormally hyperphosphorylated, which ultimately causes the microtubules to disassemble, and the free tau molecules aggregate into paired helical filaments.
Product Specifications
Background
Tau, the microtubule‐associated protein, forms insoluble filaments that accumulate as neurofibrillary tangles in Alzheimer's disease (AD) and related tauopathies. Under physiological conditions, tau regulates the assembly and maintenance of the structural stability of microtubules. In the diseased brain, however, tau becomes abnormally hyperphosphorylated, which ultimately causes the microtubules to disassemble, and the free tau molecules aggregate into paired helical filaments.
Host
HEK293
Origin Species
Mouse
Target
Tau
Conjugation
Unconjugated
Tag
Mouse IgG1 | Mouse Kappa
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.
Purity
95%
Bioactivity
Immobilized Recombinant Human p-Tau217 Protein at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human p-tau217 Antibody, Mouse IgG1 (6G7C8) (Cat. No. TAU-MY2102) with a linear range of 0.03-2 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/TAU-MY2102.pdf
Species
Mouse
CAS Number
9007-83-4
Curated Selection
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