Mesalamine impurity P
Mesalamine impurity P is an impurity of Mesalamine (HY-15027) . 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[1].
Product Specifications
CAS Number
[887256-40-8]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
NF-κB; PAK; PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mesalamine-impurity-p.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(O)C(C2=CC=C(S(=O)(O)=O)C=C2)=CC(N)=C1)O
Molecular Formula
C13H11NO6S
Molecular Weight
309.29
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Kyle Dammann, et al.PAK1 modulates a PPARγ/NF-κB cascade in intestinal inflammation.Biochim Biophys Acta. 2015 Oct;1853 (10 Pt A) :2349-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NF-κB; PAK1; PPAR
Available Sizes
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