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2'-Deoxyadenosine-5'-monophosphate-13C10 (dilithium)

2'-Deoxyadenosine-5'-monophosphate-13C10 dilithium is 13C-labeled 2'-Deoxyadenosine-5'-monophosphate. 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.

Product Specifications

UNSPSC

12352005

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/2-deoxyadenosine-5-monophosphate-13c10-dilithium.html

Solubility

10 mM in DMSO

Smiles

O=P(O[Li])(O[Li])O[13CH2][13C@H]1O[13C@@H](N2[13C]3=N[13CH]=N[13C](N)=[13C]3N=[13CH]2)[13CH2][13C@@H]1O

Molecular Formula

13C10H12Li2N5O6P

Molecular Weight

353.01

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Katsuya Narumi, et al. Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP. PLoS One. 2019 Oct 21;14 (10) :e0223892.|[3]V Duarte, et al. Insertion of dGMP and dAMP during in vitro DNA synthesis opposite an oxidized form of 7,8-dihydro-8-oxoguanine. Nucleic Acids Res. 1999 Jan 15;27 (2) :496-502.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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