Werner syndrome RecQ helicase-IN-2
Werner syndrome RecQ helicase-IN-2 (example 57) is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor and can be used in cancer research[1].
Product Specifications
CAS Number
2869954-51-6
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/werner-syndrome-recq-helicase-in-2.html
Purity
99.32
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N1CCN(CC1)C2=C(CC)N(CC(NC3=CC=C(C(F)(F)F)C=C3C)=O)C4=NC(C5=CCOCC5)=NN4C2=O)C6=NC=NC(C)=C6O
Molecular Formula
C32H34F3N9O5
Molecular Weight
681.66
References & Citations
[1]Triazolo-pyrimidine analogues for treating diseases connected to the inhibiton of werner syndrome recq helicase (wrn) . WO2022249060
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Mucin 5AC (MUC5AC) (45M1), CF740 conjugate, 0.1mg/mL
Mucin 5AC (MUC5AC) (58M1), CF647 conjugate, 0.1mg/mL
Ep-CAM / CD326 (VU-1D9), CF568 conjugate, 0.1mg/mL
Von Willebrand Factor (3E2D10), CF568 conjugate, 0.1mg/mL
Complement C4d (C4D204), CF647 conjugate, 0.1mg/mL
