ATG7-IN-2
ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B[1].
Product Specifications
CAS Number
2226227-75-2
UNSPSC
12352005
Target
Atg7; Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atg7-in-2.html
Purity
99.32
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 0.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O[C@H]1[C@](O[C@@H]([C@H]1O)COS(N)(=O)=O)([H])N2C3=NC=NC(N)=C3C(OC)=N2
Molecular Formula
C11H16N6O7S
Molecular Weight
376.35
References & Citations
[1]Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28 (19) :115681.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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