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ATG7-IN-2

ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B[1].

Product Specifications

CAS Number

2226227-75-2

UNSPSC

12352005

Target

Atg7; Autophagy

Type

Reference compound

Related Pathways

Autophagy

Applications

COVID-19-immunoregulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/atg7-in-2.html

Purity

99.32

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 0.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O[C@H]1[C@](O[C@@H]([C@H]1O)COS(N)(=O)=O)([H])N2C3=NC=NC(N)=C3C(OC)=N2

Molecular Formula

C11H16N6O7S

Molecular Weight

376.35

References & Citations

[1]Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28 (19) :115681.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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