Anti-HIV-1 gp120 Antibody

This antibody is stable for at least one year. Store lyophilized product at 4°C. After reconstitution, aliquot and store at -20°C. Avoid multiple freeze-thaw cycles.

Human immunodeficiency virus (HIV) is a retrovirus that infects CD4+ T cells, macrophages and dendritic cells leaving infected individuals susceptible to various opportunistic infections. HIV is a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses are transmitted as single-stranded, positive- sense, enveloped RNA viruses. Upon entry into a target cell, viral RNA is converted to double-stranded DNA by a virally encoded reverse transcriptase. Viral DNA is integrated into host cellular DNA by a virally encoded integrase. The virus may become latent or may continue to infect other susceptible cells.