PD-1 CHO Cell Line

PD-1 (Programmed Death Protein 1, CD279) is a transmembrane protein expressed on the surface of immune cells that binds to PD-L1 or PD-L2, inducing apoptosis of T cells and inhibiting immune responses. Cancer cells often overexpress PD-L1 or PD-L2, allowing them to suppress T cell activation, evade the host immune response, and proliferate. Thus, disrupting the PD-1 co-inhibitory pathways may be an effective approach to developing anti-cancer therapies, as well as other immune diseases like multiple sclerosis, arthritis, lupus, and type I diabetes. The overexpression of PD-1 in this cell line allows for the study of PD-1 antibodies and other novel therapeutics.

Screen and validate antibodies against PD-1 for drug discovery and researchScreen for compounds that regulate or inhibit PD-1 in a cellular contextOptimize and perform biological assays

Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage. Contact technical support at[email protected]if the cells are not frozen in dry ice upon arrival.

License DisclosureVisitbpsbioscience.com/licensefor the label license and other key information about this product.Troubleshooting GuideVisitbpsbioscience.com/cell-line-faqfor detailed troubleshooting instructions. For all further questions, please email[email protected].