SHP-2 Activating Peptide (IRS1_pY1172 (dPEG8) pY1222)
IRS1_pY1172 (dPEG8) pY1222 (SEQ: H2N-LN (pY) IDLDLV (dPEG8) LST (pY) -ASINFQK-amide)
Product Specifications
Background
It has been shown that the bisphosphorylated insulin receptor substrate 1 (IRS-1) binds to the (N) -SH2 domain of SHP-2 (PTPN11) resulting in activation of the SHP-2 enzymatic activity.
Concentration
100 µM
Purity
> 95% (by HPLC)
Shipping Conditions
-20°C
Storage Conditions
Soluble in DMSO. Store at -80oC.
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