11-Oxoisomogroside V
Selected Variant
HY-N12011-01
Size: 1 mg
11-Oxoisomogroside V (compound 3) is a cucurbitacin isolated from the crude extract of Luo Han Guo. 11-Oxoisomogroside V activates the transcriptional activity of PGC-1α. In the luciferase experiment, the results showed that 10 μM and 20 μM 11-Oxoisomogroside V could increase the luciferase activity to 133.79% and 143.81%[1].
Product Specifications
CAS Number
2149606-15-3
UNSPSC
12352005
Target
PGC-1α
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/11-oxoisomogroside-v.html
Solubility
10 mM in DMSO
Smiles
C[C@]12[C@](CC=C3[C@@]2([H])CC[C@@H](C3(C)C)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO)CO)([H])[C@]6([C@](CC1=O)([C@@](CC6)([H])[C@H](C)CC[C@H](C(C)(O)C)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)O)O)O[C@@H]9O[C@@H]([C@H]([C@@H]([C@H]9O)O)O)CO)C)C
Molecular Formula
C60H100O29
Molecular Weight
1285.42
References & Citations
[1]Niu B, et al. Cucurbitane Glucosides from the Crude Extract of Siraitia grosvenorii with Moderate Effects on PGC-1α Promoter Activity. J Nat Prod. 2017 May 26;80 (5) :1428-1435.|[2]Niu B. et al. Cucurbitane Glucosides from the Crude Extract of Siraitia grosvenorii with Moderate Effects on PGC-1α Promoter Activity. J Nat Prod. 2017 May 26;80 (5) :1428-1435.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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