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CHIR-99021 (CT99021) HCl

CHIR-99021 is a highly specific glycogen synthase kinase-3 (GSK-3) inhibitor which can inhibit both isoforms with IC50 of 10 nM (GSK-3α) and 6.7 nM (GSK-3β) .

Product Specifications

CAS Number

1797989-42-4

Purity

98%

Solubility

≥ 25.1 mg/mL in DMSO; ≥ 4.23 mg/mL in H2O; ≥ 4.83 mg/mL in EtOH.  For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while.

Molecular Formula

C22H18Cl2N8•HCl

Shipping Conditions

Room Temperature (continental US) or Gel Packs

Storage Conditions

Solid and stock solution can be stored for at least 6 months at -20°C.

Calculated Molecular Weight

501.8

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