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CHIR-99021 (CT99021)

CHIR-99021 is a highly specific glycogen synthase kinase-3 (GSK-3) inhibitor which can inhibit both isoforms with IC50 of 10 nM (GSK-3α) and 6.7 nM (GSK-3β) .This product has beencited 3 times.

Product Specifications

CAS Number

252917-06-9

Purity

≥ 97%

Format

Solid

Solubility

≥ 23.27 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O. For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Long-term storage in solution is not recommended. Not stable in diluted solutions.

Molecular Formula

C22H18Cl2N8

Shipping Conditions

Room Temperature (continental US) or Gel Packs

Storage Conditions

At least 6 months at -20°C. Avoid freeze/thaw cycles.

Calculated Molecular Weight

465.34 Da

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