Epacadostat (INCB024360)
Epacadostat (INCB024360) is an orally available hydroxyamidine and inhibitor of indoleamine 2,3- dioxygenase (IDO1), with an IC50of 10 nM. It shows little activity against other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO) . Epacadostat displays potential immunomodulating and antineoplastic activities.This product has beencited 2 times.
Product Specifications
CAS Number
1204669-58-8
Purity
≥ 98%
Format
White powder
Solubility
Soluble in DMSO.
Molecular Formula
C11H13BrFN7O4S
Shipping Conditions
-80°C
Storage Conditions
Store as supplied at or below -20°C for up to 2 years. Stable in DMSO at -80°C for up to 6 months.
Calculated Molecular Weight
438.2 Da
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