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Epacadostat (INCB024360)

Epacadostat (INCB024360) is an orally available hydroxyamidine and inhibitor of indoleamine 2,3- dioxygenase (IDO1), with an IC50of 10 nM. It shows little activity against other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO) . Epacadostat displays potential immunomodulating and antineoplastic activities.This product has beencited 2 times.

Product Specifications

CAS Number

1204669-58-8

Purity

≥ 98%

Format

White powder

Solubility

Soluble in DMSO.

Molecular Formula

C11H13BrFN7O4S

Shipping Conditions

-80°C

Storage Conditions

Store as supplied at or below -20°C for up to 2 years. Stable in DMSO at -80°C for up to 6 months.

Calculated Molecular Weight

438.2 Da

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