Ruxolitinib Phosphate
INCB018424 (Ruxolitinib) is an orally bioavailable JAK inhibitor. (IC50 values for JAK1, JAK2 and JAK3 are 3,5 and 332 nM, respectively) . INCB018424 is useful for rheumatoid arthritis.
Product Specifications
Purity
≥ 98% determined by HPLC
Format
Solid
Solubility
≥ 20.2 mg/mL in DMSO; ≥ 6.92 mg/mL in EtOH with gentle warming and ultrasonic; ≥ 8.03 mg/mL in H2O with gentle warming and ultrasonic
Molecular Formula
C17H21N6O4P
Shipping Conditions
-20°C
Storage Conditions
At least 6 months at -20°C.
Calculated Molecular Weight
404.36
CAS Number
1092939-17-7
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