Anti-Claudin-18 Isoform2-Anti-CD3 IgG Bispecific Antibody
Anti-Claudin-18 isoform2 (CLDN18.2) -Anti-CD3 IgG format bispecific antibody is a purified recombinant human bispecific antibody with T cell Engager. This bispecific antibody has been tested for specific activity in the functional reporter assay using NFAT-luc reporter Jurkat cell line (BPS Bioscience #60621) in the presence of CLDN18.2-CHO cells (BPS Bioscience #78533-H) that overexpress CLDN18.2.
Product Specifications
CAS Number
9007-83-4
UniProt
P56856
Applications
This product is for research use only. It is not suitable for human diagnostic or therapeutic use. The anti-CLDN18.2-anti-CD3 IgG format bispecific antibody can be used for studying CLDN18.2+ cancer cell-mediated T cell activation, using either primary T cells or reporter cell lines such as NFAT-luc-Jurkat cells (BPS Bioscience #60621) .
Purification
Protein A affinity
Purity
≥ 90%
Format
Aqueous buffer solution
Shipping Conditions
-80°C
Storage Conditions
At least 12 months at -80°C.
Calculated Molecular Weight
Total: 150 kDa (Heavy Chain: 50 kDa; Light Chain: 24 kDa)
Formulation
8 mM phosphate, pH 7.4,110 mM NaCl, 2.2 mM KCl, and 20% glycerol
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