Anti-Claudin-18 Isoform2-Anti-CD3 IgG Bispecific Antibody
Anti-Claudin-18 isoform2 (CLDN18.2) -Anti-CD3 IgG format bispecific antibody is a purified recombinant human bispecific antibody with T cell Engager. This bispecific antibody has been tested for specific activity in the functional reporter assay using NFAT-luc reporter Jurkat cell line (BPS Bioscience #60621) in the presence of CLDN18.2-CHO cells (BPS Bioscience #78533-H) that overexpress CLDN18.2.
Product Specifications
CAS Number
9007-83-4
UniProt
P56856
Applications
This product is for research use only. It is not suitable for human diagnostic or therapeutic use. The anti-CLDN18.2-anti-CD3 IgG format bispecific antibody can be used for studying CLDN18.2+ cancer cell-mediated T cell activation, using either primary T cells or reporter cell lines such as NFAT-luc-Jurkat cells (BPS Bioscience #60621) .
Purification
Protein A affinity
Purity
≥ 90%
Format
Aqueous buffer solution
Shipping Conditions
-80°C
Storage Conditions
At least 12 months at -80°C.
Calculated Molecular Weight
Total: 150 kDa (Heavy Chain: 50 kDa; Light Chain: 24 kDa)
Formulation
8 mM phosphate, pH 7.4,110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC880218-500 1x 500 µL
CD100 (Semaphorin-4D) (A8), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040745-500 1x 500 µL
CD45 / LCA (2B11 + PD7/26), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400633-500 1x 500 µL
Von Willebrand Factor (3E2D10), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880026-100 1x 100 µL
ACTH (Adrenocorticotrophic Hormone) (AH26), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880676-500 1x 500 µL
MUC18 / Mucin 18 / CD146 (OJ79c), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC881170-500 1x 500 µL
Vimentin (VM1170), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details