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Anti-CD19-Anti-CD3 IgG format Bispecific Antibody

Anti-CD19-Anti-CD3 IgG format bispecific antibody is a purified recombinant human bispecific antibody with T cell Engager. This bispecific antibody has been tested for specific activity in the functional reporter assay using NFAT-luc reporter Jurkat cell line (BPS Bioscience #60621) in the presence of CD19-CHO cells (BPS Bioscience #79561-H) that overexpress CD19.

Product Specifications

Applications

This product is for research use only.  It is not suitable for human diagnostic or therapeutic use. The anti-CD19-anti-CD3 IgG format bispecific antibody can be used for studying CD19+ cancer cell-mediated T cell activation, using either primary T cells or reporter cell lines such as NFAT-luc-Jurkat cells (BPS Bioscience #60621) .

Purification

Protein A affinity purification of the IgG-tag protein from HEK293 cells.

Purity

≥ 90%

Format

Aqueous buffer solution

Shipping Conditions

-80°C

Storage Conditions

At least 12 months at -80°C.

Calculated Molecular Weight

Heavy Chain: 50 kDa; Light Chain: 24 kDa

Formulation

8 mM phosphate, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol

CAS Number

9007-83-4

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