Anti-VISTA Neutralizing Antibody
This human monoclonal antibody recognizes human V-domain immunoglobulin (Ig) suppressor of T cell activation (VISTA), and neutralizes its interaction with VSIG3 (also called IGSF11) . VISTA is also known as B7-H5 or VSIR (GenBank Accession No. NM_022153) . VSIG3 is a ligand involved in cell adhesion as a VISTA binding partner. This neutralizing antibody has been functionally tested using the “VSIG-3:VISTA [Biotinylated] Inhibitor Screening Assay Kit” (BPS Bioscience #79782) .
Product Specifications
CAS Number
9007-83-4
UniProt
Q9H7M9
Applications
Format
Aqueous buffer solution
Shipping Conditions
-80°C
Storage Conditions
Store in aliquots at -80°C. Stable for at least 12 months from date of receipt.
Calculated Molecular Weight
~150 kDa
Specificity
The antibody recognizes a unique epitope on the surface of human VISTA protein. It has not been tested on other species
Formulation
8 mM phosphate pH 7.4,110 mM NaCl, 2.2 mM KCl, 20% glycerol
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