Anti-BCMA Antibody
This anti-BCMA antibody is a purified, recombinant human monoclonal antibody which recognizes the human BCMA protein. BCMA is also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17) and is expressed on the surface of plasma cells. BCMA is important for plasma cell differentiation and B cell proliferation. BCMA is a validated therapeutic target in multiple myeloma. The first anti-BCMA CAR-T cell therapy (idecabt agene vicleucel) was approved by the FDA in 2021.
Product Specifications
CAS Number
9007-83-4
UniProt
Q02223
Cross Reactivity
This antibody recognizes human BCMA. It has not been tested with other species.
Purification
Protein A affinity chromatography from HEK293 supernatants
Purity
≥ 90%
Format
Aqueous buffer solution
Shipping Conditions
-80°C
Storage Conditions
At least 12 months at -80°C.
Calculated Molecular Weight
~146 kDa (Anti-BCMA HC: 50 kDa; Anti-BCMA LC: 23 kDa)
Formulation
8 mM phosphate, pH 7.4,110 mM NaCl, 2.2 mM KCl, 20% glycerol
Frequently Asked Questions
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