SAR114137
SAR114137 is a highly effective drug with potent biological activity. SAR114137 exhibits altered amorphous content characteristics during physical processing of the crystalline active pharmaceutical ingredient. The amorphous API content of SAR114137 is significantly reduced when processed by different jet grinding techniques. SAR114137 exhibits good chemical stability in pharmaceutical formulations[1].
Product Specifications
CAS Number
[958853-11-7]
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sar114137.html
Smiles
O=C(N(CC1)CCC21CC2)N[C@H](C(NC3(C#N)CC3)=O)CC(F)(F)C
Molecular Formula
C17H24F2N4O2
Molecular Weight
354.39
References & Citations
[1]An example of how to handle amorphous fractions in API during early pharmaceutical development: SAR114137--a successful approach
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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