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SAR114137

SAR114137 is a highly effective drug with potent biological activity. SAR114137 exhibits altered amorphous content characteristics during physical processing of the crystalline active pharmaceutical ingredient. The amorphous API content of SAR114137 is significantly reduced when processed by different jet grinding techniques. SAR114137 exhibits good chemical stability in pharmaceutical formulations[1].

Product Specifications

CAS Number

[958853-11-7]

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sar114137.html

Smiles

O=C(N(CC1)CCC21CC2)N[C@H](C(NC3(C#N)CC3)=O)CC(F)(F)C

Molecular Formula

C17H24F2N4O2

Molecular Weight

354.39

References & Citations

[1]An example of how to handle amorphous fractions in API during early pharmaceutical development: SAR114137--a successful approach

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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