CD38 (Rat) Inhibitor Screening Assay Kit (Hydrolase Activity)

CD38, a differentiation antigen of B lymphocytes, is a type II integral membrane protein that functions as an ADP-ribosyl cyclase and nicotinamide adenine dinucleotide (NAD) glycohydrolase. The major enzymatic activity of CD38 is the hydrolysis of NAD. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in various cells, including pancreatic  cells. CD38 is a prognostic biomarker for acute B lymphoblastic leukemia.

CatalogNumberComponentAmountStorage100269CD38 (Rat) 1 µg-80°CAvoidmultiplefreeze/thawcycles4x CD38 hydrolase buffer3 ml-20°CCD38 substrate (ε-NAD) 50 µl-20°CApigenin (50 mM in DMSO) 10 µl-20°C79685Black 96-well plate1*The initial concentration of CD38 (Rat) is lot specific and will be indicated on the tube containing the enzyme