CDK2 Assay Kit1

Cyclin-dependent kinases (CDKs) are key regulators of the cell cycle. CDKs are active only when bound to their regulator proteins, cyclins. CDK activity is tightly controlled for successful cell division. Since abnormal cell division represents cancer pathology, controlling CDK activity has been shown as a promising therapeutic strategy. In particular, CDK2 plays an important role in DNA replication. The CDK2 Assay Kit is designed to measure CDK2/CyclinA2 activity for screening and profiling applications, using Kinase-Glo® MAX as a detection reagent. The CDK2 Assay Kit comes in a convenient 96-well format, with enough purified recombinant CDK2/CyclinA2 enzyme, CDK substrate peptide, ATP and kinase assay buffer for 100 enzyme reactions.This product has beencited 18 times.

Product Specifications

UniProt

P24941 (CDK2), P20248 (CyclinA2)

Format

Catalog #ReagentAmountStorage41101CDK2/CyclinA25 µg-80°CAvoidfreeze/ thawcycles!793345x Kinase assay buffer 11.5 ml-20°C79686ATP (500 µM) 100 µl-20°C7959810x CDK substrate peptide 1500 µl-20°C7969696-well plate, white1Room Temp.

Shipping Conditions

-80°C

Storage Conditions

Stable at least 6 months from date of receipt. when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.