CD38 Inhibitor Screening Assay Kit (Hydrolase Activity)
The CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) is designed to measure the glycohydrolase activity of CD38 for screening and profiling applications. The CD38 assay kit comes in a convenient 96-well format, with purified recombinant CD38 enzyme, its substrate N6-etheno-NAD (ε-NAD), and CD38 assay buffer for 100 enzyme reactions. In addition, the kit includes the CD38 inhibitor apigenin for use as a control inhibitor.Need us to run inhibitor screens or profile your compounds against CD38 (Hydrolase Activity) ? Check out ourImmunotherapy Biochemical Screening Services.
Product Specifications
Background
CD38, a differentiation antigen of B lymphocytes, is a type II integral membrane protein. It is also known as ADP-ribosyl cyclase and nicotinamide adenine dinucleotide (NAD) glycohydrolase. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in various cells, including pancreatic β cells. The major enzymatic activity of CD38 is the hydrolysis of NAD. CD38 is a prognostic biomarker for acute B lymphoblastic leukemia.
UniProt
P28907
Format
CatalogNumberReagentAmountStorage71277CD38, His-Tag (Human), HiP™1 µg-80°CAvoidmulitplefreeze/thawcycles!4x CD38 hydrolase buffer3 ml-20°CCD38 substrate (ε-NAD) 50 µl-20°CApigenin (50 mM DMSO) 10 µl-20°C79685Black 96-well plate1Room Temp.
Shipping Conditions
Dry Ice
Storage Conditions
Up to 6 months from date of receipt, when stored as recommended.
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