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Anti-CTLA4 Neutralizing Antibody

Neutralizing recombinant human monoclonal antibody recognizing the extracellular domain of CTLA4 and blocking binding of CTLA4 to B7.1 and B7.2. This antibody recognizes human CTLA4 but does not bind to murine CTLA4. This antibody has not been tested for cross-reactivity with other speciesThis product has beencited 2 times.

Product Specifications

CAS Number

9007-83-4

UniProt

P16410

Applications

Useful for inhibition of CTLA4:B7 interactions.

Purification

Protein A affinity chromatography from HEK293 supernatants.

Endotoxin

< 1 EU/µg

Format

Aqueous buffer solution.

Shipping Conditions

-80°C

Storage Conditions

Stable for at least 12 months at -80°C.

Calculated Molecular Weight

150 kDa

Formulation

8 mM phosphate, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol

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