Indimitecan (hydrochloride)
Indimitecan hydrochloride is a topoisomerase I (Top1) inhibitor with anticancer activities[1].
Product Specifications
CAS Number
[915303-04-7]
Product Name Alternative
LMP776 (hydrochloride)
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/indimitecan-hydrochloride.html
Smiles
O=C1C2=C(C3=C1C4=CC(OC)=C(C=C4C(N3CCCN5C=NC=C5)=O)OC)C=C6OCOC6=C2.Cl
Molecular Formula
C25H22ClN3O6
Molecular Weight
495.91
References & Citations
[1]Cinelli MA, et al. Identification, synthesis, and biological evaluation of metabolites of the experimental cancer treatment drugs indotecan (LMP400) and indimitecan (LMP776) and investigation of isomerically hydroxylated indenoisoquinoline analogues as topoisomerase I poisons. J Med Chem. 2012 Dec 27;55 (24) :10844-62.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Curated Selection
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