Indimitecan (hydrochloride)
Product Specifications
UNSPSC Description
Indimitecan hydrochloride is a topoisomerase I (Top1) inhibitor with anticancer activities[1].
Target Antigen
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/indimitecan-hydrochloride.html
Smiles
O=C1C2=C(C3=C1C4=CC(OC)=C(C=C4C(N3CCCN5C=NC=C5)=O)OC)C=C6OCOC6=C2.Cl
Molecular Weight
495.91
References & Citations
[1]Cinelli MA, et al. Identification, synthesis, and biological evaluation of metabolites of the experimental cancer treatment drugs indotecan (LMP400) and indimitecan (LMP776) and investigation of isomerically hydroxylated indenoisoquinoline analogues as topoisomerase I poisons. J Med Chem. 2012 Dec 27;55(24):10844-62.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-18350A/Indimitecan-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-18350A/
Clinical Information
Phase 1
CAS Number
915303-04-7
Curated Selection
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