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Anti-PD-1 Neutralizing Antibody1

Neutralizing recombinant murine/human chimeric antibodyrecognizing the PD-L1/PD-L2 binding region of humanPD-1. Thisantibodydoes not cross-react with mousePD-1, but does cross-react with monkey (M. fascicularis) PD-1. It has not been tested with other species.This product has beencited 15 times.

Product Specifications

CAS Number

9007-83-4

UniProt

Q15116

Immunogen

PD-L1/L2 binding region of human PD-1

Tag

None

Applications

Useful as a control inhibitor of PD-1 binding using the PD-1:PD-L1[Biotinylated] Inhibitor Screening Assay Kit, BPS Bioscience, Catalog #72003.

Purification

Protein A affinity chromatography from HEK293 supernatants.

Format

Aqueous buffer solution

Shipping Conditions

-80°C

Storage Conditions

Stable for at least 12 months at -80°C. Store diluted antibody with carrier protein (BSA 0.1 – 0.5%) at 4°C, stable for 2 weeks.

Calculated Molecular Weight

50 and 25 kDa for the heavy and light chains, respectively (150 kDa) .

Formulation

8 mM phosphate pH7.4 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.

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