CrkL Rabbit Polyclonal Antibody
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
CRKL
Swiss Prot
P46109 Human, P47941 Mouse, Q5U2U2 Rat
Cellular Locus
Cytosol, extrinsic component of postsynaptic membrane, neuromuscular junction, nucleoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human CrkL aa 1-303 / 303.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, FC
Positive Control
Concentration
1.053 mg/mL
Dilution
WB: 1:2,000 ;IF-Cell: 1:100 ;FC: 1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 34 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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