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CrkL Rabbit Polyclonal Antibody

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Crk L antibody Crk like protein antibody Crk-like protein antibody Crkl antibody CRKL_HUMAN antibody Crkol antibody HGNC:2363 antibody Oncogene CrkL antibody V crk avian sarcoma virus CT10 oncogene homolog like antibody v crk sarcoma virus CT10 oncogene homolog (avian) like antibody V crk sarcoma virus CT10 oncogene homolog avian like antibody

Abbreviation

CRKL

Swiss Prot

P46109 Human, P47941 Mouse, Q5U2U2 Rat

Cellular Locus

Cytosol, extrinsic component of postsynaptic membrane, neuromuscular junction, nucleoplasm.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human CrkL aa 1-303 / 303.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, FC

Positive Control

K-562 cell lysate, 293T cell lysate, MCF7 cell lysate, Jurkat cell lysate, HT-29 cell lysate, THP-1 cell lysate, HeLa cell lysate, A431 cell lysate, HL-60 cell lysate, C6 cell lysate, mouse thymus tissue lysate, rat thymus tissue lysate, K-562.

Concentration

1.053 mg/mL

Dilution

WB: 1:2,000 ;IF-Cell: 1:100 ;FC: 1:1,000

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 34 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

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