TNF-alpha/TNFSF2, Cynomolgus
Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine[1]. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death[2]. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse[3]. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury[4]. TNF-alpha/TNFSF2 Protein, Cynomolgus is a recombinant protein consisting of 157 amino acids (V77-L233) and is produced in E. coli.
Product Specifications
Product Name Alternative
TNF-alpha/TNFSF2 Protein, Cynomolgus, Cynomolgus, E. coli
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/tnf-alpha-protein-cynomolgus.html
Purity
97.30
Molecular Formula
102139631 (Gene_ID) P79337/NP_001272206.1 (V77-L233) (Accession)
Molecular Weight
Approximately 17.4 kDa, based on SDS-PAGE under reducing conditions.
References & Citations
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Storage Conditions
Stored at -20°C for 2 years
Scientific Category
Recombinant Proteins
Frequently Asked Questions
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