FR 75513
FR 75513 is a 1,1'-biphenyl-2,6-dicarboxylic acid diester series compound that can inhibit the contraction of the detrusor muscle of guinea pig bladder (IC50=3.3 μg/mL) . After intravenous injection of FR 75513 into anesthetized rats, it also showed strong inhibitory activity on the detrusor contraction (ID50=0.04 mg/kg) .
Product Specifications
CAS Number
127975-78-4
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fr-75513.html
Smiles
O=C(C1=C(C=C(C)C(C(OC(C)C)=O)=C1C2=C([N+]([O-])=O)C=CC=C2)O)OC
Molecular Formula
C19H19NO7
Molecular Weight
373.36
References & Citations
[1]Agents for the Treatment of Overactive Detrusor. I. Synthesis and Structure-Activity Relationships of 1, 1'-Biphenyl Derivatives
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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