5α-Pregnane-3α,20α-diol
5α-Pregnane-3α,20α-diol (Allopregnanediol) is a derivative of progesterone and is one of the various steroids secreted by the ovaries of rats. 5α-Pregnane-3α,20α-diol can significantly stimulate the release of luteinizing hormone (LH) in castrated rats that have been pre-treated with estrogen, while simultaneously inhibiting the secretion of follicle-stimulating hormone (FSH) [1].
Product Specifications
CAS Number
566-58-5
Product Name Alternative
Allopregnanediol
UNSPSC
12352211
Target
GnRH Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/5α-pregnane-3α-20α-diol.html
Smiles
C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@@H](CC2)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@@H](O)C)C
Molecular Formula
C21H36O2
Molecular Weight
320.51
References & Citations
[1]M Zanisi, et al. Effects on gonadotropin secretion of 5-alpha-pregnane-3 alpha, 20 alpha-diol, a physiological progesterone derivative. Proc Soc Exp Biol Med. 1979 May;161 (1) :66-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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