(R) - (4-NH2) -Exatecan
(R) - (4-NH2) -Exatecan is the R enantiomer of (4-NH2) -Exatecan (Compound A) . (R) - (4-NH2) -Exatecan, a topoisomerase inhibitor, is a derivative of Exatecan. (R) - (4-NH2) -Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
Product Name Alternative
(R) -AZ14170132
UNSPSC
12352005
Target
ADC Payload; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-4-nh2-exatecan.html
Smiles
NC1=CC=C2C3=C1CCCC3=C4CN5C(C4=N2)=CC([C@@](O)6CC)=C(C5=O)COC6=O
Molecular Formula
C23H21N3O4
Molecular Weight
403.43
References & Citations
[1]Howard PW, et, al. Compounds and conjugates thereof. US20200306243A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
RBBP6 (Retinoblastoma-binding Protein 6, p53-associated Cellular Protein of Testis, Proliferation Potential-related Protein, Protein P2P-R, Retinoblastoma-binding Q Protein 1, RBQ-1, P2PR, PACT, RBQ1, My038) (MaxLight 550)
