(R) - (4-NH2) -Exatecan
(R) - (4-NH2) -Exatecan is the R enantiomer of (4-NH2) -Exatecan (Compound A) . (R) - (4-NH2) -Exatecan, a topoisomerase inhibitor, is a derivative of Exatecan. (R) - (4-NH2) -Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
Product Name Alternative
(R) -AZ14170132
UNSPSC
12352005
Target
ADC Payload; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-4-nh2-exatecan.html
Smiles
NC1=CC=C2C3=C1CCCC3=C4CN5C(C4=N2)=CC([C@@](O)6CC)=C(C5=O)COC6=O
Molecular Formula
C23H21N3O4
Molecular Weight
403.43
References & Citations
[1]Howard PW, et, al. Compounds and conjugates thereof. US20200306243A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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