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(R) - (4-NH2) -Exatecan

(R) - (4-NH2) -Exatecan is the R enantiomer of (4-NH2) -Exatecan (Compound A) . (R) - (4-NH2) -Exatecan, a topoisomerase inhibitor, is a derivative of Exatecan. (R) - (4-NH2) -Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

Product Name Alternative

(R) -AZ14170132

UNSPSC

12352005

Target

ADC Payload; Topoisomerase

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/r-4-nh2-exatecan.html

Smiles

NC1=CC=C2C3=C1CCCC3=C4CN5C(C4=N2)=CC([C@@](O)6CC)=C(C5=O)COC6=O

Molecular Formula

C23H21N3O4

Molecular Weight

403.43

References & Citations

[1]Howard PW, et, al. Compounds and conjugates thereof. US20200306243A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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